中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [235]
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OAI收割 [235]
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期刊论文 [232]
会议论文 [2]
专著章节 [1]
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2024 [5]
2023 [19]
2022 [22]
2021 [16]
2020 [19]
2019 [12]
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学科主题
Pharmacolo... [7]
Chemistry [3]
Toxicology [3]
Gastroente... [1]
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浏览/检索结果:
共235条,第1-10条
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专题:上海药物研究所
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The development of logic gate-based fluorescent probes that respond to intracellular hydrogen peroxide and pH in tandem
期刊论文
OAI收割
TALANTA, 2024, 卷号: 270, 页码: 8
作者:
Han, Hai-Hao
;
Liu, Meng-Jiao
;
Zhang, Weijian
;
Sun, Lu-Lu
;
Ma, Xiuhua
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/19
Reactive oxygen species (ROS)
pH
Logic gate
Fluorescent probe
Cell imaging
Ent-labdane-type diterpene glycosides obtained from
Rubus
chingii
Hu and their inhibitory effects on PDE5A activity
期刊论文
OAI收割
FITOTERAPIA, 2024, 卷号: 173, 页码: 14
作者:
Yu, Jun-dong
;
Wang, Jing-Yi
;
Liu, Jia-yuan
;
Xu, Ye-chun
;
Zhang, Xue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
diterpene glycosides
Rubus Chingii Hu
PDE5A inhibitory activity
ent-labdane
Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Wu, Xi-Ying
;
Zhao, Ze-Yu
;
Osman, Ezzat E. A.
;
Wang, Xiao-Juan
;
Choo, Yeun-Mun
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/06
Platanus x acerifolia
Platanosides
Molecular ion networking (MoIN)
Antibacterial
Staphylococcus aureus
Enterococcus faecium
Structure -activity relationship (SAR)
Molecular docking
Target validation
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
;
Ren, Chao
;
Li, Mu-zi
;
Liu, Yi-hui
;
Yao, Ren-qi
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
Selective FRET nano probe based on carbon dots and naphthalimide-isatin for the ratiometric detection of peroxynitrite in drug-induced liver injury
期刊论文
OAI收割
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 2, 页码: 757-764
作者:
Wu, Yueci
;
Sun, Lu-Lu
;
Han, Hai-Hao
;
He, Xiao-Peng
;
Cao, Weiguo
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells
期刊论文
OAI收割
MOLECULAR PLANT, 2023, 卷号: 16, 期号: 12, 页码: 1990-2003
作者:
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10
作者:
Zhang, Yumin
;
Sun, Yuan
;
Xie, Yuanchao
;
Shang, Weijuan
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
Spectral and biodistributional engineering of deep near-infrared chromophore
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 9, 页码: 7
作者:
Dong, Yan
;
Lu, Xicun
;
Li, Yi
;
Chen, Weichao
;
Yin, Lei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Near infrared fluorophore
In vivo imaging
Molecular engineering
Biological distribution
Angiography
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Wu, Chun-mei
;
Mao, Jia-wen
;
Zhu, Jin-zhi
;
Xie, Can-can
;
Yao, Jia-ying
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
dry eye disease
DZ2002
corneal angiogenesis
immunomodulatory function
NF-kappa B
ophthalmic therapy