中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [197]
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OAI收割 [197]
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期刊论文 [196]
会议论文 [1]
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2024 [2]
2023 [19]
2022 [15]
2021 [14]
2020 [16]
2019 [14]
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Chemistry [6]
Pharmacolo... [5]
Biochemist... [1]
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浏览/检索结果:
共197条,第1-10条
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专题:上海药物研究所
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Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
Thieno[3
d ]pyrimidine derivative
Cyclin-dependent kinase 7
Small molecule inhibitor
Kinome selectivity
Triple negative breast cancer
Multi-omics reveals the attenuation of metabolic cardiomyopathy in mice by alkaloids in extracts from
Clausena
lansium
(Lour.) via the transition of gastrointestinal microbiota to an alternative homeostasis
期刊论文
OAI收割
JOURNAL OF FUNCTIONAL FOODS, 2024, 卷号: 112, 页码: 15
作者:
Shu, Chi
;
Huang, Jian-yuan
;
Yang, Gui-yuan
;
Xing, Na
;
Zhao, Yong
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/02/27
Alkaloids
Duncaniella
Girinimbine
Norleucine
Metabolic disorders
Wampee
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
;
Long, Li
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:
Zhang, Jingyu
;
Duan, Haiting
;
Gui, Renzhao
;
Wu, Mingfei
;
Shen, Liteng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/19
Acute myeloid leukemia
Bromodomain-containing protein 9
Proteolysis-targeting chimera
Orally bioavailable
Docking
Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells
期刊论文
OAI收割
MOLECULAR PLANT, 2023, 卷号: 16, 期号: 12, 页码: 1990-2003
作者:
Lin, Jia-Ling
;
Chen, Longxian
;
Wu, Wen-Kai
;
Guo, Xiao-Xiang
;
Yu, Cheng-Hui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
A novel integrated automatic strategy for amino acid composition analysis of seeds from 67 species
期刊论文
OAI收割
FOOD CHEMISTRY, 2023, 卷号: 426, 页码: 9
作者:
Ding, Yelin
;
Bi, Qirui
;
Huang, Dongdong
;
Liao, Jingmei
;
Yang, Lin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
Seeds
Amino acids
Phenyl isothiocyanate
Automatic neutral loss filtering
Original Research Response to programmed cell death protein 1 antibody in patients with Epstein-Barr virus-associated intrahepatic cholangiocarcinoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF CANCER, 2023, 卷号: 194, 页码: 9
作者:
He, Wen-Zhuo
;
Huang, Yu-Hua
;
Hu, Wan-Ming
;
Wang, Fang
;
Xu, Yu-Xia
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/11
Epstein-Barr virus
Intrahepatic cholangiocarcinoma
Programmed cell death protein 1
Immunotherapy
The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 页码: 12
作者:
Zhou, Jiashen
;
Zhang, Lin
;
Wang, Yiran
;
Song, Wenyan
;
Huang, Yuzhou
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/12/08
Acyl-ACP Reductases
Allosteric Regulation
Biosynthesis
Enantioselective Reduction
Enzyme Catalysis
Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:
Li, Cuixia
;
Wu, Yiran
;
Wang, Wenli
;
Xu, Lu
;
Zhou, Yan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Cyclodextrin-Coordinated Liposome-in-Gel for Transcutaneous Quercetin Delivery for Psoriasis Treatment
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2023, 页码: 13
作者:
Zhang, Yuqin
;
Gong, Shuqing
;
Liu, Lin
;
Shen, Huan
;
Liu, Ergang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
quercetin
hydroxypropyl-beta-cyclodextrin
liposome-in-gel
psoriasis
percutaneous delivery