中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [94]
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OAI收割 [94]
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期刊论文 [93]
会议论文 [1]
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2024 [1]
2023 [5]
2022 [6]
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2020 [4]
2019 [3]
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Chemistry [2]
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专题:上海药物研究所
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Regulating protein corona on nanovesicles by glycosylated polyhydroxy polymer modification for efficient drug delivery
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 20
作者:
Miao, Yunqiu
;
Li, Lijun
;
Wang, Ying
;
Wang, Jiangyue
;
Zhou, Yihan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/13
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR plus Human Prostate Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 18, 页码: 13280-13303
作者:
Xiang, Weiguo
;
Zhao, Lijie
;
Han, Xin
;
Xu, Tianfeng
;
Kregel, Steven
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
YCH1899, a Highly Effective Phthalazin-1(2H)-one Derivative That Overcomes Resistance to Prior PARP Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 20
作者:
Sun, Yuting
;
Yang, Hui
;
Yuan, Jiaqi
;
Wang, Limin
;
Song, Shanshan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13
作者:
Luo, Menglan
;
Wu, Qian
;
Yang, Yueyue
;
Sun, Lin
;
Huan, Xiajuan
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/30
BET inhibitor
BRD4
Bivalent inhibitor
Anticancer
The Effects of a Transgelin-2 Agonist Administered at Different Times in a Mouse Model of Airway Hyperresponsiveness
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 8
作者:
Yuan, Hong-Kai
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/08/16
transgelin-2
agonist
TSG12
administration time
asthma
airway hyperresponsiveness
Cell Membrane-Camouflaged Nanocarriers with Biomimetic Deformability of Erythrocytes for Ultralong Circulation and Enhanced Cancer Therapy
期刊论文
OAI收割
ACS NANO, 2022, 卷号: 16, 期号: 4, 页码: 6527-6540
作者:
Miao, Yunqiu
;
Yang, Yuting
;
Guo, Linmiao
;
Chen, Mingshu
;
Zhou, Xin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/08/16
RBC-derived nanocarriers
deformability
drug delivery
long circulation
tumor penetration
Tumour-derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour-homing and intracellular freeway transportation
期刊论文
OAI收割
JOURNAL OF EXTRACELLULAR VESICLES, 2022, 卷号: 11, 期号: 3, 页码: 16
作者:
Zhou, Xin
;
Miao, Yunqiu
;
Wang, Ying
;
He, Shufang
;
Guo, Linmiao
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/06/15
tumour-derived extracellular vesicles
hybrid lipid nanovesicles
tumour homing
siRNA delivery
hepatocellular carcinoma