中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [10]
西安光学精密机械研究... [7]
长春光学精密机械与物... [3]
自动化研究所 [2]
力学研究所 [1]
国家天文台 [1]
更多
采集方式
OAI收割 [25]
内容类型
期刊论文 [24]
会议论文 [1]
发表日期
2024 [1]
2023 [5]
2022 [6]
2021 [4]
2020 [3]
2019 [2]
更多
学科主题
筛选
浏览/检索结果:
共25条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
发表日期升序
发表日期降序
题名升序
题名降序
作者升序
作者降序
A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy
期刊论文
OAI收割
CANCER COMMUNICATIONS, 2024, 页码: 5
作者:
Liu, Yingqiang
;
Tong, Linjiang
;
Zhang, Mengge
;
Zhang, Qi
;
Liu, Qiupei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/13
Design and synthesis of 1H-pyrazolo[3,4-
d
]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18
作者:
Zhang, Junjie
;
Li, Yan
;
Tang, Haotian
;
Zhou, Qianqian
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Cancer immunotherapy
HPK1
Structure -based design
HPK1 inhibitor
Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20
作者:
Shi, Huanyu
;
Tang, Haotian
;
Li, Yan
;
Chen, Danqi
;
Liu, Tongchao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
Cancer immunotherapy
SAR study
HPK1 inhibitors
Quinazoline-2
5-diamine
IL-2 production
Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 115034
作者:
Song, Shukai
;
Tang, Haotian
;
Ran, Ting
;
Fang, Feng
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
SyntaLinker
Generative modelling
TBK1 inhibitor
pyrrolo[2
3-d]pyrimidine
Structure-activity relationship
Fabrication of Hierarchical Porous Metal Oxides by the HPMC- Assisted Gel Combustion Strategy: Incorporation of Nanoceria into Cookie-like Mn2O3 with Enhanced Oxidation Activity and Excellent Water Resistance
期刊论文
OAI收割
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2023, 页码: 13
作者:
Cao, Yijia
;
Li, Fujun
;
Zhang, Chi
;
Wang, Haotian
;
Zou, Zongpeng
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2023/05/19
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425
作者:
Sun, Yin
;
Tang, Haotian
;
Wang, Xiaoyan
;
Feng, Fang
;
Fan, Tiantian
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
TBK1 inhibitors
1H-pyrazolo[3
4-b]pyridine
structure-activity relationships (SARs)
immune response
cancer therapy
基于CDEM的岩石基坑爆破效果的数值模拟
期刊论文
OAI收割
工程爆破, 2022, 卷号: 28, 期号: 06, 页码: 15-24+41
作者:
任慧敏
;
冯春
;
唐昊天
;
张大帅
;
王彪
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/03/16
基坑爆破
CDEM
合理延时
炮孔间距
数值模拟
破碎尺寸
大块率
ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9
作者:
Song, Peiran
;
Bai, Gang
;
Chan, Shingpan
;
Zhang, Tao
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/04/10
Bruton's tyrosine kinase
interleukin-2-inducible T cell kinase
ASK120067
B-cell lymphoma
T-cell leukemia
Ultrafast Tm:CaYAlO4 laser with pulse regulation and saturation parameters evolution in the 2 mu m water absorption band
期刊论文
OAI收割
OPTICS AND LASER TECHNOLOGY, 2022, 卷号: 152
作者:
Cao, Xue
;
Zhu, Qiang
;
Xian, Anhua
;
Liu, Yangyu
;
Liu, Guangmiao
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/07/19
Mode-locked lasers
Mid-infrared lasers
Solid-state
Spectrum broadened