中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [26]
过程工程研究所 [13]
上海营养与健康研究... [13]
生态环境研究中心 [10]
合肥物质科学研究院 [8]
地理科学与资源研究所 [7]
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OAI收割 [145]
iSwitch采集 [6]
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期刊论文 [150]
会议论文 [1]
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2024 [7]
2023 [9]
2022 [10]
2021 [10]
2020 [14]
2019 [13]
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生物科学::普通生物... [5]
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浏览/检索结果:
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
Eliminating drug target interference with specific antibody or its F(ab′)
2
fragment in the bridging immunogenicity assay
期刊论文
OAI收割
BIOANALYSIS, 2024, 页码: 14
作者:
Deng, Xiaojie
;
Hou, Yingying
;
Yuan, Wenyi
;
Yang, Hongzhou
;
Guo, Ruowen
  |  
收藏
  |  
浏览/下载:135/0
  |  
提交时间:2024/04/09
anti-drug antibody
IgE
immunogenicity
mitigation
target interference
Extreme precipitation causes divergent responses of root respiration to nitrogen enrichment in an alpine meadow
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 912, 页码: 168568
作者:
Wang, Furong
;
Li, Tingting
;
Zhang, Ruiyang
;
Wang, Jinsong
;
Xu, Meng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/01/04
Nitrogen addition
Extreme precipitation
Root respiration
Root trait
Alpine meadow
Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:
Chen, Xuetao
;
Wu, Tingting
;
Du, Zhiyan
;
Kang, Wenjing
;
Xu, Rujun
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/02/27
BET
BD1
Bromodomain
Brain-permeable
Multiple sclerosis
A new method for spatial three-dimensional prediction of soil heavy metals contamination
期刊论文
OAI收割
CATENA, 2024, 卷号: 235, 页码: 12
作者:
Shen, Fengbei
;
Xu, Chengdong
;
Wang, Jinfeng
;
Hu, Maogui
;
Guo, Guanlin
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/02
Spatial pattern
Spatial stratified heterogeneity
Geodetector
Statistical model
Estimation uncertainty
Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16
作者:
Han, Fanghui
;
Zhao, Tingting
;
Zhang, Yanglong
;
Yun, Ying
;
Xu, Yuanyuan
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/02/19
SSTR5 antagonist
Gallbladder emptying
Cholesterol gallstones
Sevoflurane Alters Serum Metabolites in Elders and Aging Mice and Increases Inflammation in Hippocampus
期刊论文
OAI收割
JOURNAL OF INFLAMMATION RESEARCH, 2024, 卷号: 17, 页码: 1241-1253
作者:
Wang, Tingting
;
Wu, Xia
;
Zhao, Xiaoli
;
Li, Jiaqi
;
Yu, Jian
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/04/09
sevoflurane
hippocampus
neuroinflammation
RNA-seq
metabolomics
isatin
Coastal upwelling and redox variations in the northwestern Tarim Basin (northwest China) during the Middle-Late Ordovician: implication for paleo-depositional conditions of the organic matter enrichment in the Saergan Formation
期刊论文
OAI收割
FRONTIERS IN EARTH SCIENCE, 2023, 卷号: 11, 页码: 15
作者:
Zhu, Bi
;
Guo, Tingting
;
Liu, Chenhui
;
Pan, Wenqing
;
Chen, Yongquan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/14
black shale
productivity
redox conditions
source rock
paleo-ocean
Century-long variations of growing-season compound dry-hot extremes and their links with large-scale climate patterns in China
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2023, 页码: 15
作者:
Guo, Shuyao
;
Liu, Wenbin
;
Wang, Tingting
;
Wang, Hong
;
Feng, Yao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/06
century-scale
China
compound dry-hot extremes
growing-season
large-scale climate patterns
SDHI
Orthogonally Engineered Albumin with Attenuated Macrophage Phagocytosis for the Targeted Visualization and Phototherapy of Liver Cancer
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 31, 页码: 17377-17388
作者:
Dou, Wei-Tao
;
Qiu, Peng
;
Shi, Yuanyuan
;
Zhu, Ling
;
Guo, Chen
  |  
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2023/10/17