机构

• 上海药物研究所 [63]
• 昆明植物研究所 [14]
• 西北高原生物研究所 [10]
• 合肥物质科学研究院 [9]
• 金属研究所 [7]
• 成都生物研究所 [5]
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• OAI收割 [153]
• iSwitch采集 [1]

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• 会议论文 [1]

发表日期

• 2024 [1]
• 2023 [9]
• 2022 [9]
• 2021 [7]
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学科主题

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浏览/检索结果: 共154条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906 作者:  Liang, Xuewu;  Yu, Haolan;  Liang, Renwen;  Feng, Zhuanghui;  Saidahmatov, Abdusaid   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/04/09 Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 96, 页码: 5 作者:  Lian, Xuanmin;  Gao, Yue;  Li, Xuemei;  Wang, Peipei;  Tong, Lexian   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/11 2-aminopyrimidine  FLT3 inhibitors  MV4-11  FLT3 mutations   Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：59/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5 作者:  Wang, Yujie   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/19 Auristatin E  beta-Glucuronidase  Antiproliferation  Tumor microenvironment   Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 138, 页码: 22 作者:  Wang, Hanlin;  Wu, Zhaoxiao;  Cao, Yu;  Gao, Lixin;  Shao, Jiaan   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17 Metabolic stability  Four-membered heterocycles  Proteasome inhibitors  Multiple myeloma   Discovery of Novel SIRT1/2 Inhibitors with Effective Cytotoxicity against Human Leukemia Cells 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 页码: 11 作者:  Cai, Haiyan;  Wang, Yingying;  Zhang, Jing;  Wei, Zhenquan;  Yan, Teng   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/10/17 Toad venom bufadienolides and bufotoxins: An updated review 期刊论文  OAI收割 DRUG DEVELOPMENT RESEARCH, 2023, 页码: 24 作者:  Asrorov, Akmal M.;  Kayumov, Muzaffar;  Mukhamedov, Nurkhodja;  Yashinov, Ansor;  Mirakhmetova, Ziyoda   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 arenobufagin  bufadienolides  bufalin  bufotalin  cinobufagin  cinobufotalin  gamabufotalin   Synthesis and Biological Evaluation of Sclareolide-Indole Conjugates and Their Derivatives 期刊论文  OAI收割 MOLECULES, 2023, 卷号: 28, 期号: 4, 页码: 1737 作者:  Cheng, Ying;  Lyu, Xilin;  Liu, Chen;  Wang, Xiancheng;  Cheng, Jing   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27 sclareolide  indole  polyphenol  acetal  antitumor activity   Design, synthesis, and evaluation of pyrido.[3,4-b]pyrazin-2(1H)-one derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 79, 页码: 117155 作者:  Sun, Mei;  Wang, Chang;  Wang, Peipei;  Ye, Qingqing;  Zhou, Yubo   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/04/09 FLT3  FLT3-D835Y  Acute myeloid leukemia  Structure -activity relationships   Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 183-190 作者:  Liu, Meiying;  Zhou, Guizhen;  Su, Wenhong;  Gu, Yuejiao;  Gao, Mingshan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/27 KRAS mutation  SOS1-KRAS interaction  SOS1 inhibitor  combination therapy