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浏览/检索结果: 共19条，第1-10条 帮助

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Hemodynamic and Pharmacokinetic Interactions of TPN171 with Alcohol in Healthy Male Subjects 期刊论文  OAI收割
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2025, 卷号: 18, 期号: 2, 页码: 8
作者:  Cheng, Jie;  Qian, Hongjie;  Wang, Yu;  Liang, Liyu;  Xu, Wenjing
  |  收藏  |  浏览/下载：4/0  |  提交时间：2025/04/01
Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14
作者:  Liu, Jiayuan;  Zhang, Xianglei;  Chen, Guofeng;  Shao, Qiang;  Zou, Yi
  |  收藏  |  浏览/下载：32/0  |  提交时间：2024/01/16
Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221
作者:  He Yifei;  Liu Yin;  Yu Jinghua;  Cheng Huan;  Odilov Abdullajon
  |  收藏  |  浏览/下载：22/0  |  提交时间：2023/05/22
Pharmacokinetics, mass balance, and metabolism of [C-14]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13
作者:  He, Yi-fei;  Liu, Yin;  Yu, Jing-hua;  Cheng, Huan;  Odilov, Abdullajon
  |  收藏  |  浏览/下载：42/0  |  提交时间：2022/08/16
Facile and Cost-Effective Route for the Synthesis of Simmerafil 期刊论文  OAI收割
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2432-2437
作者:  Odilov, Abdullajon;  Liu, Yin;  Hu, Tianwen;  Jiang, Xiangrui;  Suo, Jin
  |  收藏  |  浏览/下载：48/0  |  提交时间：2022/01/18
A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects 期刊论文  OAI收割
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959
作者:  Qian, Hongjie;  Chen, Qian;  Lang, Liyu;  Zou, Yang;  Pu, Huahua
  |  收藏  |  浏览/下载：28/0  |  提交时间：2021/08/17
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Tian, Qian-qian;  Zhu, Yun-ting;  Diao, Xing-xing;  Zhang, Xiang-lei;  Xu, Ye-chun
  |  收藏  |  浏览/下载：37/0  |  提交时间：2020/12/24
Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease 期刊论文  OAI收割
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345
作者:  Mao, Fei;  Wang, Huan;  Ni, Wei;  Zheng, Xinyu;  Wang, Manjiong
  |  收藏  |  浏览/下载：61/0  |  提交时间：2019/01/08
Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 12, 页码: 1528-1536
作者:  Gao, Zhi-wei;  Zhu, Yun-ting;  Yu, Ming-ming;  Zan, Bin;  Liu, Jia
  |  收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08
preclinicalpharmacokineticsoftpn729maanovelpde5inhibitorandpredictionofitshumanpharmacokineticsusingapbpkmodel 期刊论文  OAI收割
actapharmacologicasinica, 2015, 卷号: 36, 期号: 12, 页码: 1528
作者:  Gao Zhiwei;  Zhu Yunting;  Yu Mingming;  Zan Bin;  Liu Jia
  |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01