中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [9]
长春应用化学研究所 [3]
大连化学物理研究所 [2]
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期刊论文 [26]
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浏览/检索结果:
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Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:
Zhang, Jingyu
;
Duan, Haiting
;
Gui, Renzhao
;
Wu, Mingfei
;
Shen, Liteng
  |  
收藏
  |  
浏览/下载:137/0
  |  
提交时间:2023/12/19
Acute myeloid leukemia
Bromodomain-containing protein 9
Proteolysis-targeting chimera
Orally bioavailable
Docking
Preparation of low-nitrogen chlorella based on proteolysis technology and pyrolysis characteristics of the products
期刊论文
OAI收割
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS, 2022, 卷号: 167, 页码: 9
作者:
Ling, Qifan
;
He, Sirong
;
Babadi, Arman Amani
;
Yuan, Chuan
;
Pan, Cheng
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/12/03
Proteolysis
Chlorella
Nitrogen removal
Alkaline protease
Py-GC-MS
Enzyme Hinders HIV-1 Tat Viral Transport and Real-Time Measured with Nanopores
期刊论文
OAI收割
ACS SENSORS, 2021, 卷号: 6, 期号: 10, 页码: 3781-3788
作者:
Wang, Han
;
Huang, Wenli
;
Wang, Yunjiao
;
Li, Wei
;
Liu, Qianshan
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/12/23
transmembrane pore
HIV-1 Tat protein
enzymatic proteolysis
copper
calcium
molecular transport
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:
Yang, Xiangbo
;
Wang, Zhijia
;
Pei, Yuan
;
Song, Ning
;
Xu, Lei
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/08/17
SHP2 degradation
Proteolysis targeting chimera (PROTAC)
Thalidomide-based heterobifunctional molecules
E3 ubiquitin ligase
CRBN
Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus
期刊论文
OAI收割
MOLECULAR MICROBIOLOGY, 2020, 页码: 20
作者:
Yang, Nana
;
Cao, Qiao
;
Hu, Shuyang
;
Xu, Chenchen
;
Fan, Ke
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
ClpXP
microbial interspecies interactions
proteolysis
Pseudomonas aeruginosa
quorum sensing
Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14
作者:
Zhang, Xin
;
Xu, Fang
;
Tong, Linjiang
;
Zhang, Tao
;
Xie, Hua
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/07/01
Epidermal growth factor receptor (EGFR)
Resistance
Proteolysis targeting chimera (PROTAC)
Protein degradation
Nuclear Localized O-Fucosyltransferase SPY Facilitates PRR5 Proteolysis to Fine-Tune the Pace of Arabidopsis Circadian Clock
期刊论文
OAI收割
MOLECULAR PLANT, 2020, 卷号: 13, 期号: 3, 页码: 446-458
作者:
Wang, Yan
;
He, Yuqing
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/03/01
circadian clock
O-fucosyltransferase
SPY
proteolysis
PRR5
Biochemical features of the adhesion G protein-coupled receptor CD97 related to its auto-proteolysis and HeLa cell attachment activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 1, 页码: 56-68
作者:
Yang, Li-yun
;
Liu, Xiao-fang
;
Yang, Yang
;
Yang, Lin-lin
;
Liu, Kai-wen
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
CD97
adhesion GPCR
auto-proteolysis
HeLa cell attachment
N-glycosylation
biochemicalfeaturesoftheadhesiongproteincoupledreceptorcd97relatedtoitsautoproteolysisandhelacellattachmentactivities
期刊论文
OAI收割
actapharmacologicasinica, 2017, 卷号: 38, 期号: 1, 页码: 56
作者:
Tang Yubo
;
Zhang Min
;
Tan Minjia
;
Cheng Shanmei
;
Xu Yechun
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
CD97
adhesion GPCR
auto-proteolysis
HeLa cell attachment
N-glycosylation