中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [58]
上海生物化学与细胞... [52]
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期刊论文 [345]
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Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Molecular basis of ClC-6 function and its impairment in human disease
期刊论文
OAI收割
SCIENCE ADVANCES, 2023, 卷号: 9, 期号: 41, 页码: 15
作者:
Zhang, Bing
;
Zhang, Sensen
;
Polovitskaya, Maya M.
;
Yi, Jingbo
;
Ye, Binglu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
Structural and mechanistic insights provided by single particle cryo-EM analysis of phosphoinositide 3-kinase (PI3Ka)
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023, 卷号: 1878, 期号: 5, 页码: 6
作者:
Vogt, Peter K.
;
Hart, Jonathan R.
;
Yang, Su
;
Zhou, Qingtong
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/10/17
Phosphoinositide 3-kinase
BYL-719
Nanobody
CXMS
Mutants
LIM domain-containing protein Ajuba inhibits chemotherapy-induced apoptosis by negatively regulating p53 stability in colorectal cancer cells
期刊论文
OAI收割
MOLECULAR ONCOLOGY, 2023, 卷号: 17, 期号: 8, 页码: 1678-1691
作者:
Xu, Beihui
;
Li, Qi
;
Zhang, Jianjun
;
Chen, Fuxiang
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
Ajuba
apoptosis
chemoresistance
colorectal cancer
p53
Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies
期刊论文
OAI收割
CELL RESEARCH, 2023, 卷号: 33, 期号: 7, 页码: 497-515
作者:
Guo, Liang
;
Mao, Qionglei
;
He, Ji
;
Liu, Xiaoling
;
Piao, Xuejiao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
Breakdown of self-incompatibility due to genetic interaction between a specific S-allele and an unlinked modifier
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 3420
作者:
Li, Yan
;
Mamonova, Ekaterina
;
Koehler, Nadja
;
van Kleunen, Mark
;
Stift, Marc
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/09/07
Arabidopsis EXECUTER1 interacts with WRKY transcription factors to mediate plastid-to-nucleus singlet oxygen signaling
期刊论文
OAI收割
PLANT CELL, 2023, 卷号: 35, 期号: 2, 页码: 827-851
作者:
Li, Yuhong
;
Liu, Hanhong
;
Ma, Tingting
;
Li, Jialong
;
Yuan, Jiarui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/07
Simulating androgen receptor selection in designer yeast
期刊论文
OAI收割
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022, 卷号: 7
作者:
Zhang, Haoran
;
Zhang, Lu
;
Xu, Yipeng
;
Chen, Shaoyong
;
Ma, Zhenyi
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/23
Androgen receptor mutations
Androgen receptor antagonists
Prostate cancer
Saccharomyces cerevisiae
Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 46, 页码: 11
作者:
Liu, Xiao
;
Zhou, Qingtong
;
Hart, Jonathan R.
;
Xu, Yingna
;
Yang, Su
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
phosphoinositide 3-kinase (PI3K)
mass spectrometry
mutants