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Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
Urbanization and urban energy eco-efficiency: A meta-frontier super EBM analysis based on 271 cities of China
期刊论文
OAI收割
SUSTAINABLE CITIES AND SOCIETY, 2024, 卷号: 101, 页码: 14
作者:
Zheng, Huazhu
;
Wu, Yongjiao
;
He, Hongming
;
Delang, Claudio O.
;
Lu, Jungang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/05
Urbanization
Urban energy eco-efficiency
TGR
Heterogeneity
China
TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1649-1664
作者:
Yang, Wen-ji
;
Han, Fang-hui
;
Gu, Yi-pei
;
Qu, Hui
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
TGR5 agonist
ulcerative colitis
intestinal epithelial cell
apoptosis
cAMP
PKA signaling pathway
c-FLIP
Reshuffling of the sediment suspension regime in the starving middle Yangtze River downstream from cascade mega-reservoirs
期刊论文
OAI收割
JOURNAL OF HYDROLOGY, 2023, 卷号: 622, 页码: 129694
作者:
Guo, Anan
;
Chen, Dong
;
He, Li
;
Peng, Yuming
;
Duan, Guanglei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/07/14
Sediment suspension regime
Cascade reservoirs
Nonequilibrium
Wash-load
Jingjiang reach
Reshuffling of the sediment suspension regime in the "starving" middle Yangtze River downstream from cascade mega-reservoirs
期刊论文
OAI收割
JOURNAL OF HYDROLOGY, 2023, 卷号: 622, 页码: 14
作者:
Guo, Anan
;
Chen, Dong
;
He, Li
;
Peng, Yuming
;
Duan, Guanglei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/09
Sediment suspension regime
Cascade reservoirs
Nonequilibrium
Wash-load
Jingjiang reach
Flow regulation controls sediment, carbon, and nutrient dynamics across the elevation gradient in the water level fluctuation zone of the Three Gorges Reservoir, China
期刊论文
OAI收割
JOURNAL OF SOILS AND SEDIMENTS, 2023, 页码: 18
作者:
Khurram, Dil
;
Tang, Qiang
;
Bao, Yuhai
;
He, Xiubin
;
Li, Jinlin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/10/31
Three Gorges Reservoir
Flow Regulation
Fluvial Sedimentation
Carbon Storage
Nutrient Translocation
Soil aggregate disintegration effects on soil erodibility in the water level fluctuation zone of the Three Gorges Reservoir, China
期刊论文
OAI收割
ENVIRONMENTAL RESEARCH, 2023, 卷号: 217, 页码: 11
作者:
Nsabimana, Gratien
;
Hong, Li
;
Yuhai, Bao
;
Nambajimana, Jean de Dieu
;
Jinlin, Li
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/02/15
Aggregate stability
Water level fluctuation
Three gorges reservoir
Disintegration rate
Soil erodibility
Soil organic matter
Sedimentary geochemistry mediated by a specific hydrological regime in the water level fluctuation zone of the Three Gorges Reservoir, China
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 页码: 19
作者:
Khurram, Dil
;
Bao, Yuhai
;
Tang, Qiang
;
He, Xiubin
;
Li, Jinlin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/02/27
Sedimentary geochemistry
Flow regulation
Suspended sediment
Water level fluctuation zone
Three Gorges Reservoir
Design and exploration of gut-restricted bifunctional molecule with TGR5 agonistic and DPP4 inhibitory effects for treating ulcerative colitis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 242, 页码: 114697
作者:
Han, Fanghui
;
Ning, Mengmeng
;
Wang, Kai
;
Gu, Yipei
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/21
Bifunctional molecule
Gut-restricted
Ulcerative colitis
TGR5
DPP4
Dam construction attenuates trace metal contamination in water through increased sedimentation in the Three Gorges Reservoir
期刊论文
OAI收割
WATER RESEARCH, 2022, 卷号: 217, 页码: 13
作者:
Bing, Haijian
;
Liu, Ye
;
Huang, Jiacong
;
Tian, Xin
;
Zhu, He
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/07/29
Trace metal contamination
Spatiotemporal variation
Sedimentary dynamics
Surface water
Fluvial sediments
Large reservoir