中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [2286]
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:  
Zhuo, Ning;  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Yin, Jianpeng
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/03/25
Exploration of the potential association between GLP-1 receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database 期刊论文  OAI收割
BMC MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 13
作者:  
Zhou, Jianxing;  Zheng, You;  Xu, Baohua;  Long, Songjun;  Zhu, Li-e
  |  收藏  |  浏览/下载:15/0  |  提交时间:2024/03/25
Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with Gs proteins 期刊论文  OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13
作者:  
  |  收藏  |  浏览/下载:21/0  |  提交时间:2024/03/13
Nanobodies as negative allosteric modulators for human calcium sensing receptor 期刊论文  OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:  
Cui, Qianqian;  Wang, Lu;  Wang, Haonan;  Chen, Xiaochen;  Han, Li
  |  收藏  |  浏览/下载:16/0  |  提交时间:2024/04/09
Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17
作者:  
Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu
  |  收藏  |  浏览/下载:9/0  |  提交时间:2024/02/27
Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20
作者:  
Yang, Wenjiao;  Gong, Xudong;  Sun, Haiguo;  Wu, Chunhui;  Suo, Jin
  |  收藏  |  浏览/下载:7/0  |  提交时间:2024/03/06
Application of ensemble learning for predicting GABAA receptor agonists 期刊论文  OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2024, 卷号: 169, 页码: 13
作者:  
Xiao, Fu;  Ding, Xiaoyu;  Shi, Yan;  Wang, Dingyan;  Wang, Yitian
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/03/25
Immunotherapy Innovations in the Fight against Osteosarcoma: Emerging Strategies and Promising Progress 期刊论文  OAI收割
PHARMACEUTICS, 2024, 卷号: 16, 期号: 2, 页码: 21
作者:  
Cheng, Shigao;  Wang, Huiyuan;  Kang, Xuejia;  Zhang, Hui
  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/04/09
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:  
Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/02/27
Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16
作者:  
Han, Fanghui;  Zhao, Tingting;  Zhang, Yanglong;  Yun, Ying;  Xu, Yuanyuan
  |  收藏  |  浏览/下载:2/0  |  提交时间:2024/02/19