机构

• 上海药物研究所 [251]

采集方式

• OAI收割 [251]

内容类型

• 期刊论文 [249]
• 会议论文 [2]

发表日期

• 2024 [5]
• 2023 [41]
• 2022 [28]
• 2021 [29]
• 2020 [18]
• 2019 [18]
• 更多

学科主题

筛选

浏览/检索结果: 共251条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 7-Dehydrocholesterol dictates ferroptosis sensitivity 期刊论文  OAI收割 NATURE, 2024, 卷号: 626, 期号: 7998, 页码: 29 作者:  Li, Yaxu;  Ran, Qiao;  Duan, Qiuhui;  Jin, Jiali;  Wang, Yanjin   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/04/09 Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15 作者:  Yan, Xue;  Zhang, Chun;  Gao, Li-Xin;  Liu, Min -Min;  Yang, Yu-Ting   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 Imidazo[124] triazole derivatives  Fluorescence property  SHP1  Bioactivity  Cellular imaging   New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9 作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Chromone  Thiazolidine-2  4-dione  Protein tyrosine phosphatase 1B  Inhibitors   A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory 期刊论文  OAI收割 INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14 作者:  Zhang, Hui;  Hu, Ke;  Lu, Yumeng;  Xu, Zhijian;  Chen, Gege   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/25 Multiple myeloma  M1 macrophages  Th1 cells  Immunomodulatory   Species discrimination of multiple botanical origins of Fritillaria species based on infrared spectroscopy, thin layer chromatography-image analysis and untargeted metabolomics 期刊论文  OAI收割 PHYTOMEDICINE, 2024, 卷号: 123, 页码: 11 作者:  An, Ya-Ling;  Li, Yun;  Wei, Wen-Long;  Li, Zhen-Wei;  Zhang, Jian-Qing   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Species discrimination  Fritillaria species  Infrared spectroscopy  Thin layer chromatography-image analysis  Untargeted metabolomics   Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12 作者:  Lin, Ting-ting;  Xiong, Wei;  Chen, Gui-hua;  He, Yang;  Long, Li   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/26 osimertinib resistance  targeted drug delivery  liposomes  panobinostat  tumor-associated macrophage  combination therapy   Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18 作者:  Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/19 Acute myeloid leukemia  Bromodomain-containing protein 9  Proteolysis-targeting chimera  Orally bioavailable  Docking   Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2023, 页码: 14 作者:  Deng, Minjie;  Gao, Yue;  Wang, Peipei;  Du, Wenjing;  Xu, Gaoya   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/19 Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/02/19 Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12 作者:  Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Protein tyrosine phosphatases inhibitors  PTP1B inhibitors  Mechanism study  Molecular dynamics