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浏览/检索结果: 共562条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10 作者:  Chen, Guofeng;  Xie, Hang;  Liu, Jiayuan;  Shao, Qiang;  Li, Minjun   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Methyl substitution  Selectivity  FABP4 inhibitor  Anti-inflammation  Metabolic stability   Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21 作者:  Zhang, Hongjin;  Lin, Guohao;  Jia, Suyun;  Zhang, Ying;  Wu, Jianbo   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/01/26 Thieno[3  d ]pyrimidine derivative  Cyclin-dependent kinase 7  Small molecule inhibitor  Kinome selectivity  Triple negative breast cancer   Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 19 作者:  Zhu, Shengnan;  Yuan, Qingning;  Li, Xinzhu;  He, Xinheng;  Shen, Shiyi   |  收藏  |  浏览/下载：99/0  |  提交时间：2024/01/16 different ligands  recognition  ligand selectivity  receptor   Development of PI3Kγ selective inhibitors: the strategies and application 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 10 作者:  Gu, Dong-Yan;  Zhang, Meng-Meng;  Li, Jia;  Zhou, Yu-Bo;  Sheng, Rong   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/08 PI3K  PI3K gamma inhibitors  isoform selectivity  drug development  rational drug design   Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15 作者:  Kong, Linghui;  Ning, Kuan;  Liu, Xiao;  Lu, Jiashuo;  Chen, Baiyu   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 N-cyclopropylmethyl nornepenthone derivatives  derivatives  Structure-activity relationship  MOR antagonist  Functional reversal  Reversal of subtype-selectivity  Opioid use disorder   Surface modification of Fe5C2 by binding silica-based ligand: A theoretical explanation of enhanced C2 oxygenate selectivity 期刊论文  OAI收割 MOLECULAR CATALYSIS, 2023, 卷号: 547, 页码: 113333 作者:  Yin, Junqing;  Wang, Shuyuan;  Xu, Dan;  You, Yong;  Liu, Xingchen   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/09/05 Surface modification  Iron carbide  Support -like ligand  Catalytic selectivity  Fischer-Tropsch Synthesis   Synthesis, and biological evaluation of EGFR/HER2-NAMPT conjugates for tumor treatment 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2023, 页码: 20 作者:  Ding, Mengyuan;  Shen, Qianqian;  Lu, Wei;  Zhu, Shulei   |  收藏  |  浏览/下载：62/0  |  提交时间：2023/10/17 EGFR  HER2  NAMPT  Resistance  Selectivity  Molecular docking   Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors 期刊论文  OAI收割 CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11 作者:  Yang, Yun;  Xiong, Yuan;  Zhu, Guanghao;  Sun, Mengru;  Zou, Kun   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 Human carboxylesterase 2 (hCES2A)  Berberine analogues  Structure -activity relationships (SAR)  Inhibition kinetics  Selectivity   Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16 作者:  He, Yulong;  Li, Shunyi;  Zhu, Yueyue;  Wang, Yujie;  Chen, Yuqi   |  收藏  |  浏览/下载：62/0  |  提交时间：2023/10/17 Structure-activity relationship  FABP4 inhibitor  Biphenyl scaffold  Selectivity  Oral bioavailability  Anti-inflammation   Porous multi-site ionic liquid composites for superior selective and reversible adsorption of ammonia 期刊论文  OAI收割 SEPARATION AND PURIFICATION TECHNOLOGY, 2023, 卷号: 310, 页码: 9 作者:  Zheng, Shuang;  Xu, Qiuxia;  Zeng, Shaojuan;  Li, Guilin;  Jiang, Haiyan   |  收藏  |  浏览/下载：1/0  |  提交时间：2023/05/19 NH3 adsorption  Ionic liquids  Porous composites  Selectivity  Multi-sites