中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
水生生物研究所 [6]
上海药物研究所 [4]
南海海洋研究所 [2]
海洋研究所 [2]
武汉植物园 [2]
生物物理研究所 [1]
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OAI收割 [17]
iSwitch采集 [2]
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期刊论文 [18]
学位论文 [1]
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2023 [1]
2022 [1]
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2019 [5]
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Fisheries;... [2]
Cell Biolo... [1]
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Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 115034
作者:
Song, Shukai
;
Tang, Haotian
;
Ran, Ting
;
Fang, Feng
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
SyntaLinker
Generative modelling
TBK1 inhibitor
pyrrolo[2
3-d]pyrimidine
Structure-activity relationship
Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425
作者:
Sun, Yin
;
Tang, Haotian
;
Wang, Xiaoyan
;
Feng, Fang
;
Fan, Tiantian
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
TBK1 inhibitors
1H-pyrazolo[3
4-b]pyridine
structure-activity relationships (SARs)
immune response
cancer therapy
Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Bao, Weilian
;
Liu, Xiaohong
;
You, Yan
;
Hou, Hui
;
Wang, Xu
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2021/11/24
SNX10
IBD
Macrophage
PIKfyve
TBK1
PPI inhibitor
Molecular characterization of a cyprinid fish (Ancherythroculter nigrocauda) TBK1 and its kinase activity in IFN regulation
期刊论文
OAI收割
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2021, 卷号: 114, 页码: 10
作者:
Chen, Jian
;
Zhou, Xiao-Yu
;
Li, Pei
;
Li, Zhuo-Cong
;
Zhang, Can
  |  
收藏
  |  
浏览/下载:133/0
  |  
提交时间:2020/12/31
TBK1
IFN
Antiviral
Ancherythroculter nigrocauda
Promoter activity
Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298
作者:
Ding, Chunyong
;
Song, Zilan
;
Shen, Ancheng
;
Chen, Tingting
;
Zhang, Ao
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
Immunotherapy
Anti-tumor
cGAS
STING
TBK1
Small molecule modulators
IKK epsilon-like plays an important role in the innate immune signaling of the Pacific oyster (Crassostrea gigas)
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 93, 页码: 551-558
作者:
Huang, Baoyu
;
Tang, Xueying
;
Zhang, Linlin
;
Li, Li
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2020/01/03
Oyster
Innate immunity
IKKe
TBK1
NF-kappa B
IRF
Zebrafish FGFR3 is a negative regulator of RLR pathway to decrease IFN expression
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 92, 期号: 1, 页码: 224-229
作者:
Liu, Shu-Bo
;
Lu, Long-Feng
;
Lu, Xiao-Bing
;
Li, Shun
;
Zhang, Yong-An
  |  
收藏
  |  
浏览/下载:169/0
  |  
提交时间:2019/10/21
FGFR3
Negative regulator
Interferon
TBK1
Zebrafish
Zebrafish FGFR3 is a negative regulator of RLR pathway to decrease IFN expression
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 92, 页码: 224-229
作者:
Liu, Shu-Bo
;
Lu, Long-Feng
;
Lu, Xiao-Bing
;
Li, Shun
;
Zhang, Yong-An
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/10/17
FGFR3
Negative regulator
Interferon
TBK1
Zebrafish
Functional Characterization of Dark Sleeper (Odontobutis obscura) TBK1 on IFN Regulation
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2019, 卷号: 10, 页码: 11
作者:
Chen, Jian
;
Li, Zhuo Cong
;
Lu, Long Feng
;
Li, Pei
;
Li, Xi-Yin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/10/17
TBK1
IFN
RLRs
antiviral
Odontobutis obscura
Host hdac4 regulates the antiviral response by inhibiting the phosphorylation of irf3
期刊论文
iSwitch采集
Journal of molecular cell biology, 2019, 卷号: 11, 期号: 2, 页码: 158-169
作者:
Yang, Qi
;
Tang, Jielin
;
Pei, Rongjuan
;
Gao, XiaoXiao
;
Guo, Jing
收藏
  |  
浏览/下载:110/0
  |  
提交时间:2019/05/08
Hdac4
Antiviral response
Irf3
Tbk1
Ikke