中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2024, 页码: 12
作者:
Zhang, Huimin
;
Xu, Dounan
;
Huang, Hongchan
;
Jiang, Hao
;
Hu, Linghao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Metabolic regulation of homologous recombination repair by MRE11 lactylation
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 2, 页码: 40
作者:
Chen, Yuping
;
Wu, Jinhuan
;
Zhai, Linhui
;
Zhang, Tingting
;
Yin, Hui
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10
作者:
Chen, Guofeng
;
Xie, Hang
;
Liu, Jiayuan
;
Shao, Qiang
;
Li, Minjun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Methyl substitution
Selectivity
FABP4 inhibitor
Anti-inflammation
Metabolic stability
RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2024, 卷号: 43, 期号: 1, 页码: 15
作者:
Lin, Ying
;
Wu, Yun
;
Zhang, Qiangzu
;
Tu, Xunwei
;
Chen, Sufang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/20
Non-small cell lung cancer
Brain metastasis
RPTOR
SPHK2
S1P
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy
期刊论文
OAI收割
THERANOSTICS, 2024, 卷号: 14, 期号: 3, 页码: 1195-1211
作者:
Zhang, Ying
;
Akhil, Venu
;
Seo, Ho Seong
;
Park, Hae Ran
;
Kim, Soo Hyun
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Cancer radiotherapy
immunogenic cell death
calreticulin
L-ASNase
reactive oxygen species
immune checkpoint inhibitor
DNA Aptamer Binding Octapeptide Repeat Region of Cellular Prion Protein
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2023, 卷号: 95, 期号: 50, 页码: 18595-18602
作者:
Sheng, Jing
;
Zhang, Nan
;
Long, Zhenhao
;
Zhang, Xiangru
;
Zu, Shuang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:
Wang, Yingcong
;
Dong, Sanfeng
;
Hu, Ke
;
Xu, Li
;
Feng, Qilin
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/01/26
Norcantharidin
Derivative
DCZ5417
TRIP13
Anti-myeloma
MAPK
SGF29 nuclear condensates reinforce cellular aging
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 21
作者:
Yan, Kaowen
;
Ji, Qianzhao
;
Zhao, Dongxin
;
Li, Mingheng
;
Sun, Xiaoyan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/12/11
Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 页码: 12
作者:
Zhou, Jiashen
;
Zhang, Lin
;
Wang, Yiran
;
Song, Wenyan
;
Huang, Yuzhou
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2023/12/08
Acyl-ACP Reductases
Allosteric Regulation
Biosynthesis
Enantioselective Reduction
Enzyme Catalysis