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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共40条，第1-10条 帮助

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Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4855-4869
作者:  Gu, Chenming;  Liu, Jiayuan;  Qian, Fei;  Yu, Wenchao;  Huang, Doudou
  |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07
Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14
作者:  Liu, Jiayuan;  Zhang, Xianglei;  Chen, Guofeng;  Shao, Qiang;  Zou, Yi
  |  收藏  |  浏览/下载：22/0  |  提交时间：2024/01/16
Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19 期刊论文  OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 18, 页码: 11
作者:  Xu, Haiyu;  Li, Shufen;  Liu, Jiayuan;  Cheng, Jinlong;  Kang, Liping
  |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17
Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 1, 页码: 228-245
作者:  Li, Heng;  Zhang, Yao;  Liu, Moting;  Fan, Chen;  Feng, Chunlan
  |  收藏  |  浏览/下载：20/0  |  提交时间：2022/06/15
PDE4B Induces Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Is Transcriptionally Suppressed by CBX7 期刊论文  OAI收割
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
作者:  Huang, Zhengnan;  Liu, Jiakuan;  Yang, Jiale;  Yan, Yilin;  Yang, Chenkai
  |  收藏  |  浏览/下载：23/0  |  提交时间：2022/06/15
Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文  OAI收割
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen
  |  收藏  |  浏览/下载：112/0  |  提交时间：2021/11/04
Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Lu, Qiu-kai;  Fan, Chen;  Xiang, Cai-gui;  Wu, Bing;  Lu, Hui-min
  |  收藏  |  浏览/下载：56/0  |  提交时间：2021/06/11
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia
  |  收藏  |  浏览/下载：32/0  |  提交时间：2021/05/24
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文  OAI收割
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu
  |  收藏  |  浏览/下载：25/0  |  提交时间：2020/12/24
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文  OAI收割
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen
  |  收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24