中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
昆明植物研究所 [2]
上海应用物理研究所 [2]
生物物理研究所 [1]
高能物理研究所 [1]
长春应用化学研究所 [1]
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OAI收割 [13]
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期刊论文 [12]
学位论文 [1]
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2024 [1]
2023 [1]
2022 [3]
2020 [1]
2019 [1]
2016 [1]
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Biochemist... [1]
Biology [1]
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AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
He, Xin-heng
;
Li, Jun-rui
;
Shen, Shi-yi
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/01/14
AlphaFold
structure-based drug design
artificial intelligence
GPCR
structural biology
Genomic and structural basis for evolution of tropane alkaloid biosynthesis
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 17, 页码: e2302448120
作者:
Wang,Yong-Jiang
;
Tain,Tian
;
Yu,Jia-Yi
;
Li,Jie
;
Xu,Bingyan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/05/09
tropane alkaloids
evolution
biosynthesis
genome
structural biology
METHYLTRANSFERASE
REVEAL
AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 7
作者:
He, Xin-heng
;
You, Chong-zhao
;
Jiang, Hua-liang
;
Jiang, Yi
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
G protein-coupled receptors
AlphaFold2
protein structure prediction
drug design
structural biology
肿瘤细胞抗凋亡调控因子c-FLIPs的结构与功能研究
学位论文
OAI收割
: 中国科学院大学, 2022
作者:
白志强
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/05/14
细胞凋亡
Apoptosis, c-FLIPS, NMR, Structural biology
c-FLIPS
核磁共振
结构生物学
Structure genomics of SARS-CoV-2 and its Omicron variant: drug design templates for COVID-19
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13
作者:
Wu, Can-rong
;
Yin, Wan-chao
;
Jiang, Yi
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/15
COVID-19
SARS-CoV-2
structural biology
omicron
drug design
vaccine development
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325
作者:
Chang, Rulue
;
Zhang, Xin
;
Qiao, Anna
;
Dai, Antao
;
Belousoff, Matthew J.
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/12/24
glucagon receptor
glucagon-like peptide-1 receptor
dual agonist
cryo-electron microscopy
single particle analysis
structure-function
structural biology
peptide 15 (P15)
metabolic disorder
G protein?coupled receptor (GPCR)
glucagon
GLP-1 receptor
A guide to sample delivery systems for serial crystallography
期刊论文
OAI收割
FEBS JOURNAL, 2019, 卷号: 286, 期号: 22, 页码: 4402-4417
作者:
Zhao, FZ
;
Zhang, B
;
Yan, EK
;
Sun, B
;
Wang, ZJ
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/10/16
X-RAY-DIFFRACTION
ROOM-TEMPERATURE
FEMTOSECOND CRYSTALLOGRAPHY
PROTEIN CRYSTALLIZATION
STRUCTURAL BIOLOGY
MILLISECOND CRYSTALLOGRAPHY
CRYSTAL-STRUCTURE
RADIATION-DAMAGE
DATA-COLLECTION
MICROCRYSTALS
The new NCPSS BL19U2 beamline at the SSRF for small-angle X-ray scattering from biological macromolecules in solution
期刊论文
OAI收割
JOURNAL OF APPLIED CRYSTALLOGRAPHY, 2016, 卷号: 49, 页码: 1428-1432
作者:
Li, N
;
Li, XH
;
Wang, YZ
;
Liu, GF
;
Zhou, P
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2017/03/02
biological small-angle X-ray scattering
automation and high brilliance
structural biology
Structural Analysis Reveals the Substrate-Binding Mechanism for the Expanded Substrate Specificity of Mutant meso-Diaminopimelate Dehydrogenase
期刊论文
OAI收割
CHEMBIOCHEM, 2015, 卷号: 16, 期号: 6, 页码: 924-929
作者:
Liu, Weidong
;
Guo, Rey-Ting
;
Chen, Xi
;
Li, Zhe
;
Gao, Xiuzhen
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2016/06/23
amination
dehydrogenases
enzyme catalysis
protein structures
structural biology
Androgen receptor: structure, role in prostate cancer and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 1, 页码: 3-23
作者:
Tan, M. H. Eileen
;
Li, Jun
;
Xu, H. Eric
;
Melcher, Karsten
;
Yong, Eu-leong
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
androgen
androgen receptor
prostate cancer
nuclear receptor
drug discovery
rational drug design
structural biology
castration resistance
antiandrogen