中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [16]
昆明植物研究所 [2]
上海生物化学与细胞生... [1]
生态环境研究中心 [1]
合肥物质科学研究院 [1]
兰州化学物理研究所 [1]
更多
采集方式
OAI收割 [22]
内容类型
期刊论文 [21]
学位论文 [1]
发表日期
2024 [1]
2023 [2]
2022 [3]
2021 [3]
2020 [2]
2019 [2]
更多
学科主题
Biotechnol... [1]
分析化学与药物化学 [1]
筛选
浏览/检索结果:
共22条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
发表日期升序
发表日期降序
题名升序
题名降序
作者升序
作者降序
Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10
作者:
Chen, Guofeng
;
Xie, Hang
;
Liu, Jiayuan
;
Shao, Qiang
;
Li, Minjun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Methyl substitution
Selectivity
FABP4 inhibitor
Anti-inflammation
Metabolic stability
Repurposed Fenoprofen Targeting SaeR Attenuates Staphylococcus aureus Virulence in Implant-Associated Infections
期刊论文
OAI收割
ACS CENTRAL SCIENCE, 2023, 页码: 20
作者:
Jiang, Feng
;
Chen, Yingjia
;
Yu, Jinlong
;
Zhang, Feiyang
;
Liu, Qian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
Synthesis and biological evaluation of pyrazole-fused oleanolic acid derivatives as novel inhibitors of inflammatory and osteoclast differentiation
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 80, 页码: 117177
作者:
Yu, Yuanyuan
;
Yuan, Wenlong
;
Yuan, Jiaqi
;
Wei, Wenhui
;
He, Qian
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
Osteoarthritis
Oleanolic acid derivatives
Anti-inflammatory
IL-1? inhibition
Antiosteoclastic activity
Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Song, Jia
;
Yang, Rui-rui
;
Chang, Jie
;
Liu, Ya-dan
;
Lu, Cheng-hao
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/11/11
cyclic GMP-AMP synthase
covalent inhibitor
inflammatory bowel disease
high-throughput screening
Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 7
作者:
Tong, Xiao
;
Chen, Li
;
He, Shi-jun
;
Zuo, Jian-ping
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/09/30
artemisinin derivative
beta-aminoarteether maleate (SM934)
autoimmune and inflammatory diseases
T helper cells
macrophages
inflammatory cytokines
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11, 页码: 7697-7716
作者:
Zhang, Shurui
;
Chen, Xiaoxu
;
Wu, Chenglin
;
Xu, Hui
;
Xie, Xiong
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/08/16
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
滇牡丹降血糖活性成分的比较分析和挖掘
学位论文
OAI收割
2021
作者:
黄骞
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/20
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:
Zhang, Rui
;
Li, Heng
;
Zhang, Xianglei
;
Li, Jian
;
Su, Haixia
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
PDE4 inhibitors
Tetrahydroisoquinoline
Antipsoriasis
Natural iridoids from Patrinia heterophylla showing anti-inflammatory activities in vitro and in vivo
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2020, 卷号: 104, 页码: 1-11
作者:
Wu, Peng
;
Song, Ziteng
;
Li, Ying
;
Wang, Huimei
;
Zhang, Han
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/09/15
Iridoids
Anti-inflammatory potency
NO inhibition
Zebrafish model
Patrinia heterophylla