中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [373]
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:  
Zhuo, Ning;  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Yin, Jianpeng
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/03/25
Safety, pharmacokinetics, and food effect of sudapyridine (WX-081), a novel anti-tuberculosis candidate in healthy Chinese subjects 期刊论文  OAI收割
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2024, 卷号: 17, 期号: 2, 页码: 10
作者:  
Yu, Chengyin;  Qian, Hongjie;  Wu, Qingqing;  Zou, Yang;  Ding, Qicheng
  |  收藏  |  浏览/下载:15/0  |  提交时间:2024/03/06
Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma 期刊论文  OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14
作者:  
Tao, Yimin
  |  收藏  |  浏览/下载:14/0  |  提交时间:2024/03/13
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:  
Cheng, Chen;  Ren, Chao;  Li, Mu-zi;  Liu, Yi-hui;  Yao, Ren-qi
  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/02/27
A NIR-II Photoacoustic/NIR-IIa Fluorescent Probe for Targeted Imaging of Glioma under NIR-II Excitation 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 3, 页码: 1861-1871
作者:  
Lyu, Shuxin;  Lu, Siyu;  Gui, Conghao;  Guo, Chunyan;  Han, Juanjuan
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/03/13
Sevoflurane Alters Serum Metabolites in Elders and Aging Mice and Increases Inflammation in Hippocampus 期刊论文  OAI收割
JOURNAL OF INFLAMMATION RESEARCH, 2024, 卷号: 17, 页码: 1241-1253
作者:  
Wang, Tingting;  Wu, Xia;  Zhao, Xiaoli;  Li, Jiaqi;  Yu, Jian
  |  收藏  |  浏览/下载:9/0  |  提交时间:2024/04/09
Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the assay of 12 substances in rat plasma and its application to rat pharmacokinetics of Epimedium and Psoraleae Fructus herb pair after oral administration 期刊论文  OAI收割
JOURNAL OF SEPARATION SCIENCE, 2024, 卷号: 47, 期号: 1, 页码: 17
作者:  
Wang, Linwei;  Yin, Xiaoying;  Liu, Huan;  Wang, Yangyang;  Li, Zhixiong
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/02/27
Safety, tolerability and pharmacokinetics of forsythin in healthy subjects: a double-blinded, placebo-controlled single-dose and multiple-dose escalation and food effect study 期刊论文  OAI收割
ANNALS OF MEDICINE, 2023, 卷号: 55, 期号: 2, 页码: 9
作者:  
Li, Cuiyun;  Wu, Min;  Zhang, Hong;  Zhu, Xiaoxue;  Fu, Li
  |  收藏  |  浏览/下载:22/0  |  提交时间:2024/01/16
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  
Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2023/12/11
Glutamine Production by Glul Promotes Thermogenic Adipocyte Differentiation Through Prdm9-Mediated H3K4me3 and Transcriptional Reprogramming 期刊论文  OAI收割
DIABETES, 2023, 卷号: 72, 期号: 11, 页码: 24
作者:  
Pan, Xiaowen;  Ye, Lingxia;  Guo, Xiaozhen;  Wang, Weihua;  Zhang, Ziyin
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/03/25