中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [411]
采集方式
OAI收割 [411]
内容类型
期刊论文 [411]
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2023 [39]
2022 [37]
2021 [23]
2020 [27]
2019 [32]
2018 [33]
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Biochemist... [2]
Pharmacolo... [2]
Immunology [1]
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浏览/检索结果:
共411条,第1-10条
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专题:上海药物研究所
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Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
;
Ren, Chao
;
Li, Mu-zi
;
Liu, Yi-hui
;
Yao, Ren-qi
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
Extracellular Matrix-Trapped Bioinspired Lipoprotein Prolongs Tumor Retention to Potentiate Antitumor Immunity
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 14
作者:
Wu, Yao
;
Li, Yongping
;
Hu, Zixin
;
Li, Yuan
;
Zhang, Shixuan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/02/27
antitumor responses
bioinspired lipoprotein
extracellular matrix
pomalidomide
tumor retention
SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Li, Wen-jing
;
Xie, Cheng-ying
;
Zhu, Xi
;
Tang, Jiao
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/02/19
SIBP-03
HER3
HER3-targeted therapy
neuregulin 1
EGFR
HER2
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:
Zhang, Jingyu
;
Duan, Haiting
;
Gui, Renzhao
;
Wu, Mingfei
;
Shen, Liteng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/19
Acute myeloid leukemia
Bromodomain-containing protein 9
Proteolysis-targeting chimera
Orally bioavailable
Docking
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
;
Liu, Chen
;
Xu, Dehua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Jin-Fu-An decoction manipulation of macrophage polarization via β-catenin (CTNNB1) synergizes with cisplatin in lung cancer
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 168, 页码: 17
作者:
Tang, Yang
;
Sun, Zhe
;
Wu, Siqi
;
Zhang, Chengyu
;
Zhang, Yanling
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/01/16
Lung cancer
Jin-Fu-An decoction
Tumor-associated macrophages
Macrophage polarization
beta-catenin
Infiltration of cytotoxic T cells
CD47 and PD-L1 overexpression in proliferating human hepatocytes attenuated immune responses and ameliorated acute liver injury in mice
期刊论文
OAI收割
AMERICAN JOURNAL OF TRANSPLANTATION, 2023, 卷号: 23, 期号: 12, 页码: 1832-1844
作者:
Ma, Chen
;
Cao, Huiying
;
Sun, Zhen
;
Deng, Qiangqiang
;
Liu, Wenjing
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/27
hepatocyte transplantation
macrophages
T cells
survival
function
Paired box 6 gene delivery preserves beta cells and improves islet transplantation efficacy
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 20
作者:
So, Wing Yan
;
Liao, Yilie
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/11
AAV
beta cells
diabetes
islet transplant
PAX6
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:
Li, Xin
;
Wu, Xiaowei
;
Nie, Shenyou
;
Zhao, Jidong
;
Yao, Yuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
MLL-rearranged leukemia
super elongation complexes
small-molecule inhibitor
protein-protein interaction
cancer therapeutics