中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [271]
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OAI收割 [271]
内容类型
期刊论文 [264]
会议论文 [7]
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2024 [2]
2023 [12]
2022 [22]
2021 [10]
2020 [11]
2019 [26]
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浏览/检索结果:
共271条,第1-10条
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专题:上海药物研究所
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A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 11
作者:
Huang, Wen-si
;
Li, Wei-qiang
;
Yu, Xiong
;
Xue, Ming-zhen
;
Yuan, Ya-li
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/04/09
Anti -gastric cancer monoclonal antibody
Ramucirumab
LC -MS/MS
Method validation
Surrogate peptide
Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10
作者:
Chen, Guofeng
;
Xie, Hang
;
Liu, Jiayuan
;
Shao, Qiang
;
Li, Minjun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
Methyl substitution
Selectivity
FABP4 inhibitor
Anti-inflammation
Metabolic stability
Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14
作者:
Liu, Jiayuan
;
Zhang, Xianglei
;
Chen, Guofeng
;
Shao, Qiang
;
Zou, Yi
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/01/16
Phosphodiesterase-4 (PDE4)
PDE5
Inhibitor
Drug repurposing
Crystal structure
Structure -guided optimization
Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2023, 卷号: 15, 期号: 706, 页码: 15
作者:
Ji, Shuyi
;
Feng, Li
;
Fu, Zile
;
Wu, Gaohua
;
Wu, Yingcheng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in cancer
期刊论文
OAI收割
CANCER CELL, 2023, 卷号: 41, 期号: 7, 页码: 1345-+
作者:
Wang, Hanling
;
Li, Ni
;
Liu, Qiuli
;
Guo, Jiacheng
;
Pan, Qiang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies
期刊论文
OAI收割
CELL RESEARCH, 2023, 卷号: 33, 期号: 7, 页码: 497-515
作者:
Guo, Liang
;
Mao, Qionglei
;
He, Ji
;
Liu, Xiaoling
;
Piao, Xuejiao
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
Proteomics of adjacent-to-tumor samples uncovers clinically relevant biological events in hepatocellular carcinoma
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 8, 页码: 17
作者:
Zhu, Hongwen
;
Lin, Youpei
;
Lu, Dayun
;
Wang, Shisheng
;
Liu, Yuejia
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
proteomics
hepatocellular carcinoma
normal tissue adjacent to tumor
heterogeneity
Paraventricular nucleus-central amygdala oxytocinergic projection modulates pain-related anxiety-like behaviors in mice
期刊论文
OAI收割
CNS NEUROSCIENCE & THERAPEUTICS, 2023, 页码: 14
作者:
Li, Yu-Jie
;
Du, Wei-Jia
;
Liu, Rui
;
Zan, Gui-Ying
;
Ye, Bing-Lu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
anxiety
central nucleus of the amygdala
oxytocin
pain
paraventricular nucleus
Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches
期刊论文
OAI收割
CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 18, 页码: 4681-4696
作者:
Shao, Qiang
;
Xiong, Muya
;
Li, Jiameng
;
Hu, Hangchen
;
Su, Haixia
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R
期刊论文
OAI收割
PROTEIN & CELL, 2023, 卷号: 14, 期号: 5, 页码: 382-386
作者:
Li, Beibei
;
Han, Shuo
;
Wang, Mu
;
Yu, Yu
;
Ma, Limin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/21