机构

• 上海药物研究所 [271]

采集方式

• OAI收割 [271]

内容类型

• 期刊论文 [264]
• 会议论文 [7]

发表日期

• 2024 [2]
• 2023 [12]
• 2022 [22]
• 2021 [10]
• 2020 [11]
• 2019 [26]
• 更多

学科主题

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浏览/检索结果: 共271条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay 期刊论文  OAI收割 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 11 作者:  Huang, Wen-si;  Li, Wei-qiang;  Yu, Xiong;  Xue, Ming-zhen;  Yuan, Ya-li   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/04/09 Anti -gastric cancer monoclonal antibody  Ramucirumab  LC -MS/MS  Method validation  Surrogate peptide   Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10 作者:  Chen, Guofeng;  Xie, Hang;  Liu, Jiayuan;  Shao, Qiang;  Li, Minjun   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Methyl substitution  Selectivity  FABP4 inhibitor  Anti-inflammation  Metabolic stability   Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14 作者:  Liu, Jiayuan;  Zhang, Xianglei;  Chen, Guofeng;  Shao, Qiang;  Zou, Yi   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/01/16 Phosphodiesterase-4 (PDE4)  PDE5  Inhibitor  Drug repurposing  Crystal structure  Structure -guided optimization   Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2023, 卷号: 15, 期号: 706, 页码: 15 作者:  Ji, Shuyi;  Feng, Li;  Fu, Zile;  Wu, Gaohua;  Wu, Yingcheng   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/10/17 Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in cancer 期刊论文  OAI收割 CANCER CELL, 2023, 卷号: 41, 期号: 7, 页码: 1345-+ 作者:  Wang, Hanling;  Li, Ni;  Liu, Qiuli;  Guo, Jiacheng;  Pan, Qiang   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies 期刊论文  OAI收割 CELL RESEARCH, 2023, 卷号: 33, 期号: 7, 页码: 497-515 作者:  Guo, Liang;  Mao, Qionglei;  He, Ji;  Liu, Xiaoling;  Piao, Xuejiao   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27 Proteomics of adjacent-to-tumor samples uncovers clinically relevant biological events in hepatocellular carcinoma 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 8, 页码: 17 作者:  Zhu, Hongwen;  Lin, Youpei;  Lu, Dayun;  Wang, Shisheng;  Liu, Yuejia   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 proteomics  hepatocellular carcinoma  normal tissue adjacent to tumor  heterogeneity   Paraventricular nucleus-central amygdala oxytocinergic projection modulates pain-related anxiety-like behaviors in mice 期刊论文  OAI收割 CNS NEUROSCIENCE & THERAPEUTICS, 2023, 页码: 14 作者:  Li, Yu-Jie;  Du, Wei-Jia;  Liu, Rui;  Zan, Gui-Ying;  Ye, Bing-Lu   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 anxiety  central nucleus of the amygdala  oxytocin  pain  paraventricular nucleus   Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches 期刊论文  OAI收割 CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 18, 页码: 4681-4696 作者:  Shao, Qiang;  Xiong, Muya;  Li, Jiameng;  Hu, Hangchen;  Su, Haixia   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R 期刊论文  OAI收割 PROTEIN & CELL, 2023, 卷号: 14, 期号: 5, 页码: 382-386 作者:  Li, Beibei;  Han, Shuo;  Wang, Mu;  Yu, Yu;  Ma, Limin   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/03/21