机构

• 上海药物研究所 [12]
• 高能物理研究所 [1]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [14]

发表日期

• 2023 [3]
• 2021 [1]
• 2020 [2]
• 2019 [1]
• 2018 [2]
• 2016 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共14条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Development of PI3Kγ selective inhibitors: the strategies and application 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 10 作者:  Gu, Dong-Yan;  Zhang, Meng-Meng;  Li, Jia;  Zhou, Yu-Bo;  Sheng, Rong   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/08 PI3K  PI3K gamma inhibitors  isoform selectivity  drug development  rational drug design   Discovery of 4-oxo-4,5-dihydropyrazolo[1,5-a]quinoxaline-7-carboxamide derivatives as PI3K alpha inhibitors via virtual screening and docking-based structure optimization 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 86, 页码: 15 作者:  Gu, Dongyan;  Zhang, Mengmeng;  Cai, Lvtao;  Wang, Chang;  Zhou, Yu -Bo   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17 PI3K alpha inhibitors  Virtual screening  Structure optimization   Root-Extracted lignanamides from Limonium gmelinii (Willd.) Kuntze with a potential PTP1B inhibitory activity by regulating PI3K/AKT signaling pathway 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 9 作者:  Tuohongerbieke, Amanguli;  Liu, Liu;  Li, Jun;  Xin, Xuelei;  Aisa, Haji Akber   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 Limonium gmelinii (Willd  ) Kuntze  Plumbaginaceae  Lignanamides  Protein tyrosine phosphatase 1B inhibitors  PI3K  AKT Signaling Pathway   Discovery of 2-(5-(quinolin-6-yl)-1,3,4-oxadiazol-2-yl)acetamide derivatives as novel PI3K alpha inhibitors via docking-based virtual screening 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 9 作者:  Gu, Dongyan;  Cheng, Gang;  Zhang, Mengmeng;  Zhou, Yu-Bo;  Li, Jia   |  收藏  |  浏览/下载：19/0  |  提交时间：2021/05/24 PI3K alpha inhibitors  Virtual screening  2-(5-(quinolin-6-yl)-1,3,4 oxadiazol-2-yl)acetamide  Molecular dynamics   Emerging roles of class I PI3K inhibitors in modulating tumor microenvironment and immunity 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8 作者:  Sun, Pu;  Meng, Ling-hua   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/12/21 phosphoinositide 3-kinase (PI3K)  PI3K inhibitors  tumor microenvironment  immune cells  immunotherapy   Design, synthesis and antiproliferative activity evaluation of a series of pyrrolo [2,1-f] [1,2,4] triazine derivatives 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 12, 页码: 4 作者:  Xiang, Hao-Yue;  Chen, Yan-Hong;  Wang, Yi;  Zhang, Xi;  Ding, Jian   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Antiproliferative  Cancer  Therapy  PI3K inhibitors  Pyrrolo [2,1-f][1,2,4] triazine  Kinase   Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors 期刊论文  OAI收割 CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 94, 期号: 6, 页码: 2013-2022 作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Wang, Yi;  Song, Kun   |  收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 PI3K alpha inhibitors  proliferation inhibition  thieno[3  2-d]pyrimidine derivatives   High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822 作者:  Wang, Jia;  Gong, Grace Qun;  Zhou, Yan;  Lee, Woo-Jeong;  Buchanan, Christina Maree   |  收藏  |  浏览/下载：84/0  |  提交时间：2019/01/08 high throughput screening  PI3 kinase  PI3K alpha H1047R  inhibitors  molecular modeling   Bi2S3-Tween 20 Nanodots Loading PI3K Inhibitor, LY294002, for Mild Photothermal Therapy of LoVo Cells In Vitro and In Vivo 期刊论文  OAI收割 ADVANCED HEALTHCARE MATERIALS, 2018, 卷号: 7, 期号: 22, 页码: 1800830 作者:  Gu, Z.;  Song L(宋丽);  Dong XH(董兴华);  Zhu S(朱双);  Yin WY(尹文艳)   |  收藏  |  浏览/下载：52/0  |  提交时间：2019/10/11 Bi2S3-Tween 20 nanodots  LY294002  mild photothermal therapy  photothermal-resistant  PI3K inhibitors   Characterization of selective and potent PI3K delta inhibitor (PI3KD-IN-015) for B-Cell malignances 期刊论文  OAI收割 ONCOTARGET, 2016, 卷号: 7, 期号: 22, 页码: 32641-32651 作者:  Liu, Xiaochuan 收藏  |  浏览/下载：19/0  |  提交时间：2017/11/16 Pi3k Delta  Leukemia  B-cell Malignances  Pi3k  Kinase Inhibitors