中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [44]
自动化研究所 [4]
心理研究所 [3]
海洋研究所 [3]
烟台海岸带研究所 [3]
计算技术研究所 [2]
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OAI收割 [67]
内容类型
期刊论文 [65]
学位论文 [2]
发表日期
2023 [67]
学科主题
Biochemist... [2]
Cell Biolo... [2]
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天文学 [1]
天文学::天体物理学 [1]
天文学::天体物理学... [1]
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浏览/检索结果:
共67条,第1-10条
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发表日期:2023
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Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
;
Long, Li
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:
Zhang, Jingyu
;
Duan, Haiting
;
Gui, Renzhao
;
Wu, Mingfei
;
Shen, Liteng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/12/19
Acute myeloid leukemia
Bromodomain-containing protein 9
Proteolysis-targeting chimera
Orally bioavailable
Docking
Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16694-16703
作者:
Fu, Yixian
;
Huang, Yahui
;
Zhou, Chenchen
;
Li, Xinge
;
Dong, Guoqiang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/01/26
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
;
Liu, Chen
;
Xu, Dehua
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/19
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Preparation of Multifunctional Seaweed Polysaccharides Derivatives Composite Hydrogel to Protect Ultraviolet B-Induced Photoaging In Vitro and In Vivo
期刊论文
OAI收割
MACROMOLECULAR BIOSCIENCE, 2023, 页码: 16
作者:
Wu, Yumeng
;
Geng, Lihua
;
Zhang, Jingjing
;
Wu, Ning
;
Yang, Yue
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/07
alginate oligosaccharides
multifunctional composite hydrogel
photoaging
sulfated galactofucan polysaccharides
ultraviolet B
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:
Feng, Qilin
;
Hu, Ke
;
Hu, Huifang
;
Lu, Yumeng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
DLBCL
ROS
DNA damage
JNK
Mitochondrial dysfunction
Rational design of oral delivery nanosystems for hypoglycemic peptides
期刊论文
OAI收割
NANO TODAY, 2023, 卷号: 53, 页码: 19
作者:
Peng, Taoxing
;
Shao, Xinyue
;
Long, Li
;
Liu, Han
;
Song, Wenqin
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/01/16
Hypoglycemic peptides
Oral delivery
Mucus penetration
Endocytosis
Intracellular trafficking
Exocytosis
Whole-Genome Re-sequencing and Transcriptome Reveal Candidate Genes and Pathways Associated with Hybrid Sterility in Hermaphroditic
Argopecten
Scallops
期刊论文
OAI收割
MARINE BIOTECHNOLOGY, 2023, 卷号: 25, 期号: 6, 页码: 891-906
作者:
Yu, Tieying
;
Ning, Junhao
;
Wang, Fukai
;
Liu, Guilong
;
Wang, Quanchao
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Hermaphroditic Argopecten scallops
Hybrid sterility
Gametogenesis
Meiosis and mitosis
Apoptosis